AVAPRO (irbesartan) is an angiotensin II receptor (AT1 subtype) antagonist.
Irbesartan does not inhibit ACE or renin or affect other hormone receptors or ion channels known to be involved in the cardiovascular regulation of blood pressure and sodium homeostasis.
AVAPRO may be administered with other antihypertensive agents and with or without food.
Aldosterone plasma concentrations generally decline following irbesartan administration, but serum potassium levels are not significantly affected at recommended doses. In hypertensive patients, angiotensin II receptor inhibition following chronic administration of irbesartan causes a 1.5- to 2-fold rise in angiotensin II plasma concentration and a 2- to 3-fold increase in plasma renin levels.
In healthy subjects, single oral irbesartan doses of up to 300 mg produced dose-dependent inhibition of the pressor effect of angiotensin II infusions.
Find patient medical information for Avapro Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings.
Check the labels on all your medicines (such as cough -and-cold products, diet aids, or NSAIDs such as ibuprofen, naproxen ) because they may contain ingredients that could increase your blood pressure or worsen your heart failure. Ask your pharmacist for more details.
Before having surgery, l your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).
l your doctor if your condition does not improve or if it worsens (for example, your blood pressure readings increase).
Subscribe to the WebMD Daily, and you'll get today's top health news and trending topics, and the latest and best information from WebMD.
Selected from data included with permission and ed by First Databank, Inc.
Avapro (irbesartan) is an angiotensin II receptor antagonist used to treat high blood pressure (hypertension). Avapro is sometimes given together with other blood pressure medications. Avapro is also used to treat kidney problems caused by type 2 (non-insulin-dependent) diabetes.
Call your doctor at once if you have a serious side effect such as:
You may report side effects to FDA at 1-800-FDA-1088. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.
The following important adverse reactions are described elsewhere in the labeling:
You may report side effects to FDA at 1-800-FDA-1088. Call your doctor for medical advice about side effects. This is not a complete list of side effects and others may occur.
oval, white, imprinted with 2773, HEART.
Irbesartan use was not associated with an increased incidence of dry cough, as is typically associated with ACE inhibitor use.
Irbesartan (Avapro), a drug used to treat high blood pressure and diabetic nephropathy (kidney disease). Information includes side effects, dosage, and.
Read more: How to Lower Blood Pressure: Exercise Tips (Pictures).
How much do you know about sex, love, and the human body?. The body. The bedroom. The brain.
How would you like a stronger immune system or better sleep? Action between the sheets can help you get all of this and more.
Use the pill identifier tool on RxList.
The most common side effects of irbesartan are:
What is irbesartan, and how does it work (mechanism of action)?
home / high blood pressure center / high blood pressure a-z list / irbesartan index / irbesartan, avapro drug monograph.
He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.
Drug information on Avapro (irbesartan), includes drug pictures, side effects, drug interactions, directions for use, symptoms of overdose, and what to avoid.
Visit the FDA MedWatch website or call 1-800-FDA-1088. You are encouraged to report negative side effects of prescription drugs to the FDA.
What is the most important information I should know about irbesartan (Avapro)?
What is irbesartan (Avapro)?
If you are being treated for high blood pressure, keep using this medication even if you feel well. High blood pressure often has no symptoms.
Less serious side effects may include:
Before you take irbesartan, l your doctor if you have kidney or liver disease, congestive heart failure, or if you are dehydrated.
Do not use potassium supplements or salt substitutes while you are taking irbesartan, unless your doctor has told you to.
Irbesartan is used to treat high blood pressure (hypertension).