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Buspar (Buspirone) Side Effects, Interactions, Warning, Dosage

6.16.2017 | Logan Blare

Buspirone hydrochloride tablets, USP are an antianxiety agent that is not chemically or pharmacologically related to the benzodiazepines.

In a study in normal volunteers, concomitant administration of buspirone and haloperidol resulted in increased serum haloperidol concentrations. The clinical significance of this finding is not clear.

[see Inhibitors and Inducers of Cytochrome P450 3A4 (CYP3A4) ]

Sweating, heart pounding or racing, cold, clammy hands, dry mouth, dizziness, lightheadedness, paresthesias (tingling in hands or feet), upset stomach, hot or cold spells, frequent urination, diarrhea, discomfort in the pit of the stomach, lump in the throat, flushing, pallor, high resting pulse and respiration rate.

However, mild depressive symptoms are common in GAD.

Buspirone Oral Uses, Side Effects, Interactions, Pictures, Warnings

7.17.2017 | Jennifer Bargeman

Find patient medical information for Buspirone Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings.

Ask your doctor when to start or stop taking this medication. Taking MAO inhibitors with this medication may cause a serious (possibly fatal) drug interaction. Most MAO inhibitors should also not be taken for two weeks before and after treatment with this medication. Avoid taking MAO inhibitors ( isocarboxazid, linezolid, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, selegiline, tranylcypromine ) during treatment with this medication.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so.


5.15.2017 | Logan Miers

Buspirone, brand name Buspar, is an anxiolytic drug that is primarily used to treat generalized anxiety disorder (GAD). It is also commonly used to augment.

It preferentially blocks inhibitory presynaptic D 2 autoreceptors, and antagonizes postsynaptic D 2 receptors only at higher doses. Buspirone has also been found to bind with high affinity to the D 3 and D 4 receptors (K i = 98 nM and 29 nM, respectively). In addition to the 5-HT 1A receptor, buspirone is a weak antagonist of the dopamine D 2 receptor (K i = 240 nM), with approximay 15-fold lower affinity for this receptor relative to the 5-HT 1A receptor. In accordance, buspirone has been found to increase dopaminergic neurotransmission in the nigrostriatal pathway at low doses, whereas at higher doses, postsynaptic D 2 receptors are blocked and antidopaminergic effects such as hypoactivity and reduced stereotypy, though notably not catalepsy, are observed in animals.

Structural analogues of buspirone include tandospirone, gepirone, and perospirone.

It is not uncommon for a very low-dose benzodiazepine to be prescribed in addition to buspirone, for treating acute episodes if/when they occur (buspirone's constant anxiolytic effect greatly reduces the minimum effective dose of benzodiazepines and barbiturates and therefore makes them significantly more-tolerable for use at work/driving/performing other activities which require the patient's full cognitive capacity).

Buspirone Side Effects, Dosage, Uses & More

12.22.2017 | Logan Blare

Buspirone is an oral medication used to treat anxiety disorders. Learn about side effects, warnings, dosage, and more.

If your symptoms are severe, call 9-1-1 or go to the nearest emergency room right away. If you think you’ve taken too much of this drug, call your doctor or local poison control center.

This can be harmful or prevent the drug from working well. An interaction is when a substance changes the way a drug works. Buspirone can interact with other medications, vitamins, or herbs you may be taking.

The kidneys of older adults may not work as well as they used to. As a result, more of a drug stays in your body for a longer time.

Buspirone Uses, Dosage, Side Effects

8.18.2017 | Nathan Becker

Buspirone is used to treat symptoms of anxiety, such as fear, tension, irritability and dizziness. Learn about side effects, interactions and indications.

See also: Side effects (in more detail).

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Usual Pediatric Dose for Anxiety:

Store at room temperature away from moisture, heat, and light.

Taking this medicine with other drugs that make you sleepy or slow your breathing can worsen these effects. Ask your doctor before taking buspirone with a sleeping pill, narcotic pain medicine, muscle relaxer, or medicine for anxiety, depression, or seizures.

Other brands: BuSpar, Vanspar.

shortness of breath; or.

Your doctor may occasionally change your dose to make sure you get the best results.