Lopressor, metoprolol tartrate USP, is a selective beta2-adrenoreceptor blocking agent, available in 5- mL ampuls for intravenous administration. Each ampul.
However, greater sensitivity of some elderly individuals taking Lopressor cannot be categorically ruled out. Therefore, in general, it is recommended that dosing proceed with caution in this population. Other reported clinical experience in myocardial infarction has not identified differences in response between the elderly and younger patients. In worldwide clinical trials of Lopressor in myocardial infarction, where approximay 478 patients were over 65 years of age (0 over 75 years of age), no age-related differences in safety and effectiveness were found.
The safety and efficacy of Lopressor in pediatric patients have not been established.
Lopressor, metoprolol tartrate USP, is a selective beta1-adrenoreceptor blocking agent, available as 50- and 100-mg tablets for oral administration. Metoprolol.
Absorption: The estimated oral bioavailability of immediate release metoprolol is about 50% because of pre-systemic metabolism which is saturable leading to non-proportionate increase in the exposure with increased dose.
Renal impairment : The systemic availability and half-life of Lopressor in patients with renal failure do not differ to a clinically significant degree from those in normal subjects.
Sick-sinus syndrome. Hypersensitivity to Lopressor and related derivatives, or to any of the excipients; hypersensitivity to other beta blockers (cross sensitivity between beta blockers can occur).
Risk of Anaphylactic Reactions.
Use During Major Surgery.
Relative beta 1 selectivity is demonstrated by the following: (1) In healthy subjects, Lopressor is unable to reverse the beta 2 -mediated vasodilating effects of epinephrine.
Metoprolol is used with or without other medications to treat high blood pressure (hypertension). Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. This medication is also used to treat chest pain (angina) and to improve survival after a heart.
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Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. Metoprolol is used with or without other medications to treat high blood pressure ( hypertension ). This medication is also used to treat chest pain ( angina ) and to improve survival after a heart attack.
Smoking may worsen this effect.
Pictures of Lopressor (Metoprolol Tartrate), drug imprint information, side effects for the patient.
Version: 15.02. Revision date: 10/22/2012. Cerner Multum, Inc.
Read the Lopressor (metoprolol tartrate) Side Effects Center for a complete guide to possible side effects.
You should not use this medication if you are allergic to metoprolol, or if you have a serious heart problem such as heart block, sick sinus syndrome, or slow heart rate.
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Stopping suddenly may make your condition worse. Do not stop taking metoprolol without first talking to your doctor.
Metoprolol may impair your thinking or reactions.
Easy to read patient leaflet for Lopressor. Includes indications, proper use, special instructions, precautions, and possible side effects.
Check with your doctor if any of these most COMMON side effects persist or become bothersome:. All medicines may cause side effects, but many people have no, or minor, side effects.
l your doctor if you have a history of overactive thyroid. Lopressor may hide symptoms of overactive thyroid (eg, fast heartbeat). Do not suddenly stop taking Lopressor; suddenly stopping Lopressor could worsen your condition. Your doctor should slowly lower your dose over several weeks if you need to stop taking it. Check with your doctor for more information.
Some medical conditions may interact with Lopressor.