Cyclobenzaprine is a muscle relaxant. It works by blocking nerve impulses (or pain sensations) that are sent to your brain.
Do not use cyclobenzaprine if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.
Other brands: Flexeril, Amrix, Fexmid.
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Do not crush, chew, break, or open an extended-release capsule. Swallow it whole.
Other drugs may interact with cyclobenzaprine, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide. This list is not complete.
pounding heartbeats or fluttering in your chest; or.
Stop using this medicine and call your doctor at once if you have:
blurred vision, dry mouth or throat, altered sense of taste; or.
agitation, hallucinations, fever, overactive reflexes, nausea, vomiting, diarrhea, loss of coordination, fainting.
Usual Geriatric Dose for Muscle Spasm:
Cyclobenzaprine is used together with rest and physical therapy to treat skeletal muscle conditions such as pain or injury.
Take the medicine at the same time each day.
You should not use cyclobenzaprine if you are allergic to it, or if you have:
To make sure cyclobenzaprine is safe for you, l your doctor if you have: liver disease; glaucoma; enlarged prostate; or problems with urination.
Get emergency medical help if you have any signs of an allergic reaction to cyclobenzaprine: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Sciatica acetaminophen, Tylenol, naproxen, aspirin, ibuprofen, diclofenac, Voltaren, Flexeril, Aleve, Advil, Ecotrin, Naprosyn, More.
You may have unpleasant withdrawal symptoms when you stop taking cyclobenzaprine after long-term use. Ask your doctor how to avoid withdrawal symptoms when you stop using this medicine.
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l your doctor if you are pregnant or plan to become pregnant during treatment. Cyclobenzaprine is not expected to harm an unborn baby.
Cyclobenzaprine may also be used for purposes not listed in this medication guide.
Approval History Calendar Drug history at FDA.
nausea, upset stomach, constipation.
Initial dose: 5 mg orally 3 times a day. Based on individual patient response, the dose may be increased to either 7.5 mg or 10 mg 3 times a day. Alternate doses include the 15 mg extended release capsule or 30 mg extended release capsule orally once a day.
Do not take extra medicine to make up the missed dose. Skip the missed dose if it is almost time for your next scheduled dose. Take the missed dose as soon as you remember.
Do not take this medicine in larger or smaller amounts or for longer than recommended. Follow all directions on your prescription label. Cyclobenzaprine is usually taken once daily for only 2 or 3 weeks.
severe drowsiness, fast heart rate; tremors or shaking;
See also: Side effects (in more detail).
Usual Adult Dose for Muscle Spasm:
Availability Rx Prescription only.
Because most muscle relaxants and antispasmodic drugs can cause anticholinergic adverse events, sedation, and weakness, and because their effectiveness at doses tolerated by elderly people is questionable, cyclobenzaprine meets the Beers criteria as a medication that is potentially inappropriate for use in older adults. Extended release formulations are not recommended for use in elderly patients. The manufacturer suggests an initial dose in the elderly of 5 mg, titrating slowly upward based on individual patient response.
Usual Pediatric Dose for Muscle Spasm:
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Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. This is not a complete list of side effects and others may occur.
Based on individual patient response, the dose may be increased to either 7.5 mg or 10 mg 3 times a day. Pediatric patients 15 years of age and older: Initial dose: 5 mg orally 3 times a day.
Older adults may be more sensitive to the side effects of this medication.
l your doctor if you are breast-feeding a baby. It is not known whether cyclobenzaprine passes into breast milk or if it could harm a nursing baby.
See also: Dosage Information (in more detail).
Store at room temperature away from moisture, heat, and light.
Common cyclobenzaprine side effects may include: headache, dizziness; drowsiness, tired feeling; trouble concentrating;
Pregnancy Category B No proven risk in humans.
Be careful if you drive or do anything that requires you to be alert. This medication may impair your thinking or reactions.
This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. To view content sources and attributions, please refer to our editorial policy. Data sources include Micromedex (updated June 2nd, 2017), Cerner Multum (updated June 5th, 2017), Wolters Kluwer (updated June 6th, 2017) and others. provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products.
a heart rhythm disorder, or you have recently had a heart attack; congestive heart failure; heart block; or a thyroid disorder.
Follow your doctor's instructions. Cyclobenzaprine is only part of a complete program of treatment that may also include rest, physical therapy, or other pain relief measures.
CSA Schedule N Not a controlled drug.
Generic Name: cyclobenzaprine (sye kloe BEN za preen) Brand Names: Amrix, Comfort Pac with Cyclobenzaprine, Fexmid, Flexeril.
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MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine. Do not use cyclobenzaprine if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur.
Avoid drinking alcohol. Dangerous side effects could occur.
Seek emergency medical attention or call the Poison Help line at. An overdose of cyclobenzaprine can be fatal.
Ask your doctor before taking cyclobenzaprine with a sleeping pill, narcotic pain medicine, prescription cough medicine, a muscle relaxer, or medicine for anxiety, depression, or seizures. Taking cyclobenzaprine with other drugs that make you sleepy or slow your breathing can cause dangerous or life-threatening side effects.
You should not use cyclobenzaprine if you have a thyroid disorder, heart block, congestive heart failure, a heart rhythm disorder, or you have recently had a heart attack.Cyclobenzaprine