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Meridia (Sibutramine Hydrochloride Monohydrate) Side Effects

7.16.2017 | Logan Miers

Each MERIDIA capsule contains 5 mg, 10 mg, and 15 mg of sibutramine hydrochloride monohydrate. It also contains as inactive ingredients:.

Urogenital System: abnormal ejaculation, hematuria, impotence, increased urinary frequency, micturition difficulty, urinary retention.

Urogenital System: menstrual disorders. Other Adverse Events.

Obese Patients in Placebo-Controlled Studies BODY SYSTEM Adverse Event Sibutramine (n = 2068) % Incidence Placebo (n = 884) % Incidence BODY AS A WHOLE Headache 30.3 18.6 Back pain 8.2 5.5 Flu syndrome 8.2 5.8 Injury accident 5.9 4.1 Asthenia 5.9 5.3 Abdominal pain 4.5 3.6 Chest pain 1.8 1.2 Neck pain 1.6 1.1 Allergic reaction 1.5 0.8 CARDIOVASCULAR SYSTEM Tachycardia 2.6 0.6 Vasodilation 2.4 0.9 Migraine 2.4 2.0 Hypertension/increased blood pressure 2.1 0.9 Palpitation 2.0 0.8 DIGESTIVE SYSTEM Anorexia 13.0 3.5 Constipation 11.5 6.0 Increased appetite 8.7 2.7 Nausea 5.9 2.8 Dyspepsia 5.0 2.6 Gastritis 1.7 1.2 Vomiting 1.5 1.4 Rectal disorder 1.2 0.5 METABOLIC & NUTRITIONAL Thirst 1.7 0.9 Generalized edema 1.2 0.8 MUSCULOSKELETAL SYSTEM Arthralgia 5.9 5.0 Myalgia 1.9 1.1 Tenosynovitis 1.2 0.5 Joint disorder 1.1 0.6 NERVOUS SYSTEM Dry mouth 17.2 4.2 Insomnia 10.7 4.5 Dizziness 7.0 3.4 Nervousness 5.2 2.9 Anxiety 4.5 3.4 Depression 4.3 2.5 Paresthesia 2.0 0.5 Somnolence 1.7 0.9 CNS stimulation 1.5 0.5 Emotional lability 1.3 0.6 RESPIRATORY SYSTEM Rhinitis 10.2 7.1 Pharyngitis 10.0 8.4 Sinusitis 5.0 2.6 Cough incr ease 3.8 3.3 Laryngitis 1.3 0.9 SKIN & APPENDAGES Rash 3.8 2.5 Sweating 2.5 0.9 Herpes simplex 1.3 1.0 Acne 1.0 0.8 SPECIAL SENSES Taste perversion 2.2 0.8 Ear disorder 1.7 0.9 Ear pain 1.1 0.7 UROGENITAL SYSTEM Dysmenorrhea 3.5 1.4 Urinary tract infection 2.3 2.0 Vaginal monilia 1.2 0.5 Metrorrhagia 1.0 0.8.

Concomitant use of MERIDIA (sibutramine hydrochloride monohydrate) and other agents that may raise blood pressure or heart rate have not been evaluated.

Meridia (discontinued) Uses, Dosage, Side Effects

3.12.2017 | Logan Miers

Meridia (sibutramine) was withdrawn from the U.S. market in October 2010. Meridia is used together with diet and exercise to treat obesity that may be related to diabetes, high cholesterol, or high blood pressure. l your doctor about all prescription and over-the-counter.

a bleeding or blood clotting disorder;

Meridia should not be taken for longer than 2 years.

If you have any of these other conditions, you may need to adjust your dose of Meridia or have special tests: glaucoma; high blood pressure; depression; underactive thyroid;

Do not use Meridia if you have taken an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) in the last 14 days.


9.18.2017 | Jessica MacAdam

Sibutramine is an oral anorexiant. Until 2010 it was marketed and prescribed as an adjunct in It was sold under a variety of brand names including Reductil, Meridia, Siredia, and Sibutrex. It is classified as a Schedule IV controlled substance.

Symptoms that require urgent medical attention are seizures, problems urinating, abnormal bruising or bleeding, melena, hematemesis, jaundice, fever and rigors, chest pain, hemiplegia, abnormal vision, dyspnea and edema.

Therefore, regular monitoring needs to be performed. Sibutramine can substantially increase blood pressure and heart rate in some patients.

The concomitant use of sibutramine and monoamine oxidase inhibitors (MAOIs, such as selegiline ) is not indicated, as it may increase the risk of serotonin syndrome, a somewhat rare but serious adverse drug reaction.


11.20.2017 | Jessica MacAdam

Meridia, Lady of Infinite Energies, also known as the Glister Witch, is an obscure Daedric Prince, associated with the energies of living things. Meridia has a.

An emblem representing Meridia.

The Ring of Khajiiti, as seen in Oblivion.

Eventually, after making use of its power too freely, Rajhin was abandoned by the Ring and left exposed to his enemies. It is even said that Rajhin stole a tattoo from the neck of Empress Kintyra as she slept. The Ring was originally owned by Mephala, until it was stolen off her arm by Rajhin, the renowned burglar who later became revered as the Thief God of the Khajiit. Using the Ring's powers, Rajhin became the most successful burglar in Elsweyr's history.

The Ring of Khajiiti (sometimes just Ring of Khajiit or Ring of the Khajiiti ) is an ancient Daedric artifact, many centuries old, dating back to at least the Second Era.

Weight Loss Drug Meridia Off the Market at FDA's Request

10.19.2017 | Logan Blare

Unapproved drugs, often sold as supplements, are frequently found to contain various amounts of sibutramine, the active ingredient in Meridia.

"Meridia's continued availability is not justified when you compare the very modest weight loss that people achieve on this drug to their risk of heart attack or stroke, " said John Jenkins, MD, director of FDA's drug evaluation branch.

The trial, called SCOUT, enrolled overweight and obese patients with risk factors for serious heart disease. But Abbott expected the study to show that even these patients benefited from the drug. Most of these patients would not be prescribed Meridia in the U.S. However, European drug regulators insisted that Abbott carry out a postmarketing clinical trial to evaluate heart risk.

The label falsely says the product is "100% herbal." The mislabeled drug was distributed in Chicago at the Mexican Independence Day parade and may be distributed at other community events.

Abbott strongly disagrees with the FDA's evaluation of Meridia but says it will comply with the federal agency's request.

Coincidentally, the FDA today warned that a "supplement" called Slimming Beauty Bitter Orange Slimming Capsules contains dangerous amounts of sibutramine.