Lozol (indapamide) is indicated for the treatment of hypertension, alone or in combination with other antihypertensive drugs. Lozol (indapamide) is also indicated for the treatment of salt and fluid retention associated with congestive heart failure.
The adult starting indapamide dose for hypertension is 1.25 mg as a single daily dose taken in the morning. If the response to 2.5 mg is not satisfactory after four weeks, the daily dose may be increased to 5.0 mg taken once daily, but adding another antihypertensive should be considered. If the response to 1.25 mg is not satisfactory after four weeks, the daily dose may be increased to 2.5 mg taken once daily.
Keep out of the reach of children.
Mean Changes from Baseline after 8 Weeks of Treatment – 1.25 mg Serum Electrolytes (mEq/L) Potassium Sodium Chloride Serum Uric Acid (mg/dL) BUN (mg/dL) Indapamide 1.25 mg (n= – 0.28 – 0.63 – 2.60 0.69 1.46 Placebo (n= 0.00 – 0.11 – 0.21 0.06 0.06.
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Periodic determinations of serum electrolytes should be performed at appropriate intervals.
Lozol official prescribing information for healthcare professionals. Includes: indications, dosage, adverse reactions, pharmacology and more.
The oral administration of 2.5 mg (two 1.25 mg tablets) of indapamide to male subjects produced peak concentrations of approximay 115 ng/mL of the drug in blood within two hours. A minimum of 70% of a single oral dose is eliminated by the kidneys and an additional 23% by the gastrointestinal tract, probably including the biliary route. Indapamide is the first of a new class of antihypertensive/diuretics, the indolines. The oral administration of 5 mg (two 2.5 mg tablets) of indapamide to healthy male subjects produced peak concentrations of approximay 260 ng/mL of the drug in the blood within two hours.
This medication is used to treat high blood pressure. Indapamide is also used to reduce extra fluid in the body (edema) caused by heart failure. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems.
Make sure lab personnel and all your doctors know you use this drug. This medication may interfere with certain lab tests (including parathyroid function), possibly causing false test results.
l your doctor if your condition does not get better or if it gets worse (your blood pressure readings remain high or increase).
Before using potassium supplements or salt substitutes containing potassium, consult your doctor or pharmacist. This medication may decrease your level of potassium in the blood.
If you also take certain drugs to lower your cholesterol (bile acid-binding resins such as cholestyramine or colestipol ), take indapamide at least 4 hours before or at least 4 hours after these medications.
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This is not a complete list of possible side effects.
Easy to read patient leaflet for Lozol. Includes indications, proper use, special instructions, precautions, and possible side effects.
You must talk with your healthcare provider for complete information about the risks and benefits of using Lozol. This is only a brief summary of general information about Lozol. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Lozol. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition.
Indapamide (Lozol [Discontinued]) is a drug prescribed for the treatment of high blood pressure and edema from congestive heart failure.
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Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99. Dr. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996.
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What are the uses for indapamide?
Marks, MD, is a board-certified internist and gastroenterologist.