ACCUPRIL (quinapril hydrochloride) is the hydrochloride salt of quinapril, the ethyl ester of a non-sulfhydryl, angiotensin-converting enzyme.
Call your doctor at once if you have a serious side effect such as:
These effects are usually reversible. In patients who are elderly, volume-depleted (including those on diuretic therapy), or with compromised renal function, co-administration of NSAIDs, including selective COX-2 inhibitors, with ACE inhibitors, including quinapril, may result in deterioration of renal function, including possible acute renal failure. Monitor renal function periodically in patients receiving quinapril and NSAID therapy.
The antihypertensive effect of ACE inhibitors, including quinapril may be attenuated by NSAIDs.
postmarketing trials that, combined, enrolled over 3,000 black patients and over 19,000 non-blacks, angioedema was reported in 0.30% and 0.55% of blacks (in study 1 and 2 respectively) and 0.39% and 0.17% of non-blacks.
Quinapril is used to treat high blood pressure. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. This medication is also used to treat heart failure. Quinapril belongs to a class of drugs known as ACE inhibitors.
Do not store in the bathroom. Keep all medications away from children and pets. Store at room temperature away from light and moisture.
In the US.
Take your next dose at the regular time. If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip themissed dose. Do not double the dose to catch up.
See also Precautions section.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.
Some products that may interact with this drug include: aliskiren, gold injections, lithium, sacubitril, certain drugs that weaken the immune system /increase the risk of infection (such as everolimus, sirolimus ), drugs that may increase the level of potassium in the blood (such as ARBs including losartan / valsartan, birth control pills containing drospirenone).
For the treatment of high blood pressure, it may take 1 to 2 weeks before you get the full benefit of this medication.
What is quinapril (Accupril)? Quinapril is an ACE inhibitor. ACE stands for angiotensin converting enzyme. Quinapril is used to treat high blood pressure (hypertension) and heart failure.
High blood pressure often has no symptoms. If you are being treated for high blood pressure, keep using this medication even if you feel well. You may need to use blood pressure medication for the rest of your life.
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Your doctor may occasionally change your dose to make sure you get the best results.
High blood pressure often has no symptoms.
Get information on quinapril (Accupril) ACE inhibitor drug side effects, drug interactions, warning and precautions, and pregnancy safety.
In the kidney, the narrowing caused by angiotensin II decreases blood flow and increases the arterial filtration pressure in the kidney. The enlargement of the arteries elsewhere in the body also makes it easier for the heart to pump blood. Quinapril was approved by the FDA in November 1991. ACE inhibitors are used for treating high blood pressure and heart failure and for preventing kidney failure due to high blood pressure and diabetes. In the kidneys ACE inhibitors increase blood flow and reduce the filtration pressure in the kidneys.
Accupril (quinapril) is an ACE inhibitor. ACE stands for angiotensin converting enzyme. Accupril is used to treat high blood pressure (hypertension) and heart.
Approval History 10+ years FDA approved 1991.
Usual Adult Dose for Left Ventricular Dysfunction:
Other drugs may interact with quinapril, including prescription and over-the-counter medicines, vitamins, and herbal products. l each of your health care providers about all medicines you use now and any medicine you start or stop using.
To make sure Accupril is safe for you, l your doctor if you have:
Accupril may also be used for purposes not listed in this medication guide.
Take Accupril exactly as prescribed by your doctor.