Tiazac official prescribing information for healthcare professionals. Includes: indications, dosage, adverse reactions, pharmacology and more.
As the daily dose of Tiazac capsules was increased from 120 to 540 mg, there was a more than proportional increase in diltiazem plasma concentrations as evidenced by an increase of AUC, C max and C min of 6.8, 6 and 8.6 times, respectively, for a 4.5 times increase in dose. Tiazac demonstrates non-linear pharmacokinetics.
Tiazac produces antihypertensive effects both in the supine and standing positions. No reflex tachycardia is associated with the chronic antihypertensive effects. Postural hypotension is infrequently noted upon suddenly assuming an upright position.
A study that compared patients with normal hepatic function to patients with cirrhosis who received immediate-release diltiazem found an increase in diltiazem elimination half-life and a 69% increase in bioavailability in the hepatically impaired patients.
Tiazac (diltiazem hydrochloride) is a calcium ion cellular influx inhibitor (slow channel blocker). Chemically, diltiazem hydrochloride is 1.
Decreases in blood pressure associated with diltiazem hydrochloride therapy may occasionally result in symptomatic hypotension.
However, skin eruptions progressing to erythema multiforme and/or exfoliative dermatitis have also been infrequently reported. Dermatological events (see ADVERSE REACTIONS ) may be transient and may disappear despite continued use of diltiazem hydrochloride. Should a dermatologic reaction persist, the drug should be discontinued.
Tiazac (diltiazem hydrochloride) Extended-Release Capsules.
Tiazac (diltiazem hydrochloride) Extended-release Capsules.
Storage conditions: Store at 25°C (77°F); excursions permitted to 15-30°C (59-86°F).
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Before taking diltiazem, l your doctor or pharmacist if you are allergic to it; or if you have any other allergies. Talk to your pharmacist for more details. This product may contain inactive ingredients, which can cause allergic reactions or other problems.
Ask your pharmacist about using those products safely. Check the labels on all your medicines (such as cough -and-cold products, diet aids, nonsteroidal anti-inflammatory drugs- NSAIDs such as ibuprofen for pain/fever reduction) because they may contain ingredients that could increase your blood pressure or heart rate.
Be sure to l your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).
Diltiazem belongs to a family of medications known as calcium channel blockers. It is used alone or with other medications to treat high blood pressure and angina (chest pain). It works by relaxing blood vessels and by reducing the workload of the heart.
The recommended dose of diltiazem can range from 30 mg to 360 mg daily. Swallow the capsules whole with fluids. The dose for the tablet form of diltiazem is usually taken 3 or 4 times a day. The dose for the capsule form of diltiazem is usually taken once daily. Do not chew, or crush, or open the capsules.
If you become pregnant while taking this medication, contact your doctor immediay. Pregnancy: Women who are or may become pregnant should not take diltiazem.
The starting dose to treat high blood pressure is usually 180 mg to 240 mg daily.
Tiazac XC: Diltiazem belongs to a family of medicines known as calcium channel blockers. Diltiazem extended release tablets are used to treat high blood.
There may be an interaction between diltiazem extended release tablets and any of the following:
Stop taking the medication and seek immediate medical attention if any of the following occur:
Kidney function: People with reduced kidney function or kidney disease should discuss with their doctor how this medication may affect their medical condition, how their medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Some people may experience side effects other than those listed.