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Cytoxan (Cyclophosphamide) Side Effects, Interactions, Warning

5.16.2017 | Noah Becker

Cytoxan (cyclophosphamide) is a synthetic antineoplastic drug chemically related to the nitrogen mustards. The chemical name for.

Metabolism and Nutrition: hyponatremia, fluid retention, blood glucose increased, blood glucose decreased.

Vascular: pulmonary embolism, venous thrombosis, vasculitis, peripheral ischemia, hypertension, hypotension, flushing, hot flush.

Gastrointestinal: gastrointestinal hemorrhage, acute pancreatitis, colitis, enteritis, cecitis, stomatitis, constipation, parotid gland inflammation.

Included as part of the PRECAUTIONS section.

When cyclophosphamide is included in combined cytotoxic regimens, it may be necessary to reduce the dose of cyclophosphamide as well as that of the other drugs.

Cyclophosphamide is indicated for the treatment of biopsy proven minimal change nephrotic syndrome in pediatrics patients who failed to adequay respond to or are unable to tolerate adrenocorticosteroid therapy.

Table 1: Reconstitution for Direct Intravenous Injection Strength Volume of 0.9% Sodium Chloride Cyclophosphamide Concentration 500 mg 25 mL 20 mg per mL 1 g 50 mL 2 g 100 mL Reconstitution of Cyclophosphamide.

Hematologic: myelosuppression, bone marrow failure, disseminated intravascular coagulation and hemolytic uremic syndrome (with thrombotic microangiopathy ).

Cytoxan (cyclophosphamide) can cause myelosuppression ( leukopenia, neutropenia, thrombocytopenia and anemia ), bone marrow failure, and severe immunosuppression which may lead to serious and sometimes fatal infections, including sepsis and septic shock.

Cytoxan Oral Uses, Side Effects, Interactions, Pictures, Warnings

10.21.2017 | Jessica MacAdam

Find patient medical information for Cytoxan Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings.

Save your medicine, check interactions, sign up for FDA alerts, create family profiles and more.

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Before using this medication, l your doctor or pharmacist your medical history, especially of: liver disease, kidney disease, surgery to remove your adrenal glands.

Enter the shape, color, or imprint of your prescription or OTC drug. Our pill identification tool will display pictures that you can compare to your pill.

Do not have immunizations / vaccinations without the consent of your doctor.

Common Side Effects of Cytoxan (Cyclophosphamide) Drug Center

6.17.2017 | Logan Miers

Find a comprehensive guide to possible side effects including common and rare side effects when taking Cytoxan (Cyclophosphamide) for.

Musculoskeletal and Connective Tissue: rhabdomyolysis, scleroderma, muscle spasms, myalgia, arthralgia.

Infections: The following manifestations have been associated with myelosuppression and immunosuppression caused by cyclophosphamide: increased risk for and severity of pneumonias (including fatal outcomes), other bacterial, fungal, viral, protozoal and, parasitic infections; reactivation of latent infections, (including viral hepatitis, tuberculosis ), Pneumocystis jiroveci, herpes zoster, Strongyloides, sepsis and septic shock.

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Reproductive System: infertility, ovarian failure, ovarian disorder, amenorrhea, oligomenorrhea, testicular atrophy, azoospermia, oligospermia.

Immune: immunosuppression, anaphylactic shock and hypersensitivity reaction.

Gastrointestinal: gastrointestinal hemorrhage, acute pancreatitis, colitis, enteritis, cecitis, stomatitis, constipation, parotid gland inflammation.

Endocrine: water intoxication.

Investigations: blood lactate dehydrogenase increased, C-reactive protein increased.

General Disorders and Administrative Site Conditions: multiorgan failure, general physical deterioration, influenza -like illness, injection/infusion site reactions ( thrombosis, necrosis, phlebitis, inflammation, pain, swelling, erythema ), pyrexia, edema, chest pain, mucosal inflammation, asthenia, pain, chills, fatigue, malaise, headache.

Congenital, Familial and Genetic: intra-uterine death, fetal malformation, fetal growth retardation, fetal toxicity (including myelosuppression, gastroenteritis ).

Read the entire detailed patient monograph for Cytoxan (Cyclophosphamide).

Get emergency medical help if you have any of these signs of an allergic reaction : hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Psychiatric: confusional state.

Cytoxan Indications, Side Effects, Warnings

8.19.2017 | Logan Miers

Easy to read patient leaflet for Cytoxan. Includes indications, proper use, special instructions, precautions, and possible side effects.

CSA Schedule N Not a controlled drug.

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This may not be a complete list of all interactions that may occur. Ask your health care provider if Cytoxan may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blood in urine; bloody or black tarry stools; chest pain; chills; fever; hallucinations; increased or decreased urination; infection; lower back or abdominal pain; pain, swelling, or redness at the injection site; painful urination; persistent cough; pneumonia; red, swollen, or blistered skin; seizures; severe stomach pain; shortness of breath; sore throat; sores in the mouth; swelling of the hands or feet; unusual bruising or bleeding; unusual or severe tiredness or weakness; yellowing of the skin or eyes.

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Acute Lymphocytic Leukemia prednisone, methotrexate, cyclophosphamide, Deltasone, vincristine, More.

Cytoxan is an antineoplastic.

Cyclophosphamide (Cytoxan) Cancer Drug Side Effects

4.15.2017 | Jessica MacAdam

Explains the medication cyclophosphamide (Cytoxan), a drug used for the treatment of several types of cancers and often in combination with.

Visit the FDA MedWatch website or call 1-800-FDA-1088. Cyclophosphamide increases the occurrence of heart failure that is caused by doxorubicin ( Adriamycin ), increases the action of blood thinners such as warfarin (Coumadin), and decreases the effectiveness of quinolone antibiotics ciprofloxacin ( Cipro, Cipro XR, Proquin XR). Medically Reviewed by a Doctor on 6/17/2016 Quick Guide Pancreatic Cancer Symptoms, Causes, and Treatment Report Problems to the Food and Drug Administration You are encouraged to report negative side effects of prescription drugs to the FDA.

Learn how to prevent skin cancer and how to check for melanoma, basal cell carcinoma, and squamous cell carcinoma.