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Other medications can affect the removal of propafenone from your body, which may affect how propafenone works. Examples include asunaprevir, desipramine, ketoconazole, orlistat, phenobarbital, phenytoin, rifampin, and certain HIV protease inhibitors (such as ritonavir, tipranavir ), among others.
Before taking propafenone, l your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
If you notice other effects not listed above, contact your doctor or pharmacist. This is not a complete list of possible side effects.
This medication is used to treat certain types of serious (possibly fatal) irregular heartbeat (such as paroxysmal supraventricular tachycardia and atrial fibrillation ). It is used to restore normal heart rhythm and maintain a regular, steady heartbeat. Propafenone is known as an anti-arrhythmic drug. It works by blocking the activity of certain electrical signals in the heart that can cause an irregular heartbeat. Treating an irregular heartbeat can decrease the risk for blood clots, and this effect can reduce your risk of heart attack or stroke.
Keep all medications away from children and pets. Store at room temperature away from light and moisture. Do not store in the bathroom.
Before using this medication, l your doctor or pharmacist your medical history, especially of: breathing problems (such as asthma, chronic bronchitis, emphysema ), kidney problems, liver problems, myasthenia gravis, a certain inherited heart condition ( Brugada Syndrome ).
Dizziness, headache, metallic/salty taste in the mouth, nausea / vomiting, constipation, anxiety, and tiredness may occur. If any of these effects persist or worsen, l your doctor or pharmacist promptly.
Before having surgery, l your doctor or dentist that you are using this medication.
Ask your doctor or pharmacist for more details. Grapefruit can increase the chance of side effects with this medicine. Avoid eating grapefruit or drinking grapefruit juice while using this medication unless your doctor or pharmacist says you may do so safely.
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Use this medication regularly to get the most benefit from it. To help you remember, take it at the same times each day.
l your doctor right away if any of these rare but very serious side effects occur: signs of infection (such as high fever, severe chills, weakness, persistent sore throat ), signs of liver problems (such as persistent nausea / vomiting, stomach / abdominal pain, yellowing eyes / skin, dark urine), worsening symptoms of heart failure (such as ankle /leg swelling, increased tiredness, increased shortness of breath when lying down).
QT prolongation can rarely cause serious (rarely fatal) fast/ irregular heartbeat and other symptoms (such as severe dizziness, fainting ) that need medical attention right away. Propafenone may cause a condition that affects the heart rhythm (QT prolongation).
Talk to your doctor about using propafenone safely. Low levels of potassium or magnesium in the blood may also increase your risk of QT prolongation. This risk may increase if you use certain drugs (such as diuretics /" water pills ") or if you have conditions such as severe sweating, diarrhea, or vomiting.
See also Warning section.
During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.
If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip themissed dose and resume your usual dosing schedule. Do not double the dose to catch up.
Seek immediate medical attention if any of these rare but serious side effects occur: fainting, faster/more irregular heartbeat, severe dizziness.
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2016 First Databank, Inc. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.Information last revised November 2016. Do not flush medications down the toilet or pour them into a drain unless instructed to do so.
Before using propafenone, l your doctor or pharmacist of all the drugs you take and if you have any of the following conditions: certain heart problems ( heart failure, slow heartbeat, QT prolongation in the EKG ), family history of certain heart problems (QT prolongation in the EKG, sudden cardiac death). The risk of QT prolongation may be increased if you have certain medical conditions or are taking other drugs that may cause QT prolongation.
Consult your doctor for more details. Laboratory and/or medical tests (such as EKG ) should be performed periodically to monitor your progress or check for side effects.
This drug may make you dizzy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit alcoholic beverages.
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Many drugs besides propafenone may affect the heart rhythm (QT prolongation), including amiodarone, dofetilide, flecainide, pimozide, procainamide, quinidine, sotalol, macrolide antibiotics (such as clarithromycin, erythromycin ), and certain quinolone antibiotics (such as sparfloxacin), among others. (See also Precautions section.).
However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching /swelling (especially of the face/ tongue /throat), severe dizziness, trouble breathing. A very serious allergic reaction to this drug is rare.
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Take this medication by mouth with or without food, usually every 8 hours or as directed by your doctor.
Propafenone can slow down the removal of other medications from your body, which may affect how they work. Examples of affected drugs include digoxin, imipramine, metoprolol, propranolol, warfarin, among others.
In the US.
l your doctor if your condition does not improve or if it worsens.
This medication passes into breast milk and may have undesirable effects on a nursing infant. Consult your doctor before breast -feeding.
Do not share this medication with others.
GENERIC NAME(S): Propafenone. Sign up to receive WebMD's award-winning content delivered to your inbox.
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If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. US residents can call their local poison control center at. Symptoms of overdose may include: severe dizziness, very slow heartbeat, new irregular heartbeat, fainting. Otherwise, call a poison control center right away. Canada residents can call a provincial poison control center.
This document does not contain all possible drug interactions. Do not start, stop, or change the dosage of any medicines without your doctor's approval. Drug interactions may change how your medications work or increase your risk for serious side effects. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist.
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In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at.
You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. Call your doctor for medical advice about side effects.
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Therefore, when starting treatment with this drug, your doctor may recommend that you stay in the hospital for proper monitoring and emergency medical treatment if needed. Talk with your doctor about the benefits and risks of taking this medication. Though this medication often gives great benefits to people with irregular heartbeat, it may rarely cause a serious new irregular heartbeat.
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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else.
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Older adults may be more sensitive to the side effects of this drug, especially QT prolongation (see above).
Many people using this medication do not have serious side effects. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects.Rythmol