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Zofran (Ondansetron Hydrochloride Tablets and Solution) Side

5.5.2017 | Jessica MacAdam

The active ingredient in ZOFRAN Tablets and ZOFRAN Oral Solution is ondansetron hydrochloride (HCl) as the dihydrate, the racemic form.

The coadministration of ondansetron had no effect on the pharmacokinetics and pharmacodynamics of temazepam.

ZOFRAN ODT Orally Disintegrating Tablets: Manufactured for : GlaxoSmithKline, Research Triangle Park, NC 27709. September 2014. GlaxoSmithKline, Research Triangle Park, NC 27709. ZOFRAN Tablets and Oral Solution: GlaxoSmithKline, Research Triangle Park, NC 27709. by Catalent UK Swindon Zydis Ltd., Blagrove, Swindon, Wiltshire, UK SN5 8RU.

The empirical formula is C 18 H 19 N 3 O•HCl•2H 2 O, representing a molecular weight of 365.9.

For daily fractionated radiotherapy to the abdomen, one 8-mg ZOFRAN Tablet or one 8-mg ZOFRAN ODT Tablet or 10 mL (2 teaspoonfuls equivalent to 8 mg of ondansetron) of ZOFRAN Oral Solution should be administered 1 to 2 hours before radiotherapy, with subsequent doses every 8 hours after the first dose for each day radiotherapy is given.

The recommended oral dosage is one 8-mg ZOFRAN Tablet or one 8-mg ZOFRAN ODT Tablet or 10 mL (2 teaspoonfuls equivalent to 8 mg of ondansetron) of ZOFRAN Oral Solution given 3 times a day.

Pediatric Use : There is no experience with the use of ZOFRAN Tablets, ZOFRAN ODT Tablets, or ZOFRAN Oral Solution in the prevention of radiation -induced nausea and vomiting in pediatric patients.

ZOFRAN Tablets, 8 mg (ondansetron HCl dihydrate equivalent to 8 mg of ondansetron), are yellow, oval, film-coated tablets engraved with “Zofran” on one side and “8” on the other in daily unit dose packs of 3 tablets ( NDC, and bottles of 30 tablets ( NDC.

Ondansetron does not itself appear to induce or inhibit the cytochrome P-450 drug-metabolizing enzyme system of the liver (see CLINICAL PHARMACOLOGY, Pharmacokinetics ).

Zofran Oral Uses, Side Effects, Interactions, Pictures, Warnings

7.7.2017 | Logan Miers

This medication is used alone or with other medications to prevent nausea and vomiting caused by cancer drug treatment (chemotherapy) and radiation therapy. It is also used to prevent and treat nausea and vomiting after surgery. To prevent nausea after surgery, take ondansetron by.

To help you remember, take it at the same times each day. Ondansetron may be taken up to 3 times a day for 1 to 2 days after your chemotherapy or radiation treatment is finished. If you are taking this medication on a prescribed schedule, take it regularly in order to get the most benefit from it. Take any other doses as directed by your doctor.

To minimize dizziness and lightheadedness, get up slowly when rising from a sitting or lying position.

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In the US.

Consult your doctor before breast -feeding.


6.6.2017 | Nathan Becker

Ondansetron, marketed under the brand name Zofran, is a medication used to prevent nausea and vomiting caused by cancer chemotherapy, radiation therapy.

A study of over 600,000 pregnancies in Denmark found that ondansetron during pregnancy was not associated with a significantly increased risk of spontaneous abortion, stillbirth, major birth defect, preterm birth, low birth weight, or small for gestational age. Other studies concluded that there is an increase in major congenital malformations due to an increase in heart problems among the babies. Animal reproduction studies have not shown evidence of harm to the baby or impairment of fertility with use of high daily doses of ondansetron.

There is tentative evidence that it may be useful in decreasing the desired effects of alcohol.

Zofran Uses, Dosage & Side Effects

8.8.2017 | Noah Becker

Zofran (ondansetron) blocks the actions of chemicals in the body that can trigger nausea and vomiting. Zofran is used to prevent nausea and vomiting that may be caused by surgery, cancer chemotherapy, or radiation treatment. You should not use Zofran if you are allergic to.

Get emergency medical help if you have signs of an allergic reaction to Zofran: rash, hives; fever, chills, difficult breathing; swelling of your face, lips, tongue, or throat.

Availability Rx Prescription only.

Nausea / Vomiting, Postoperative ondansetron, metoclopramide, Reglan, Emend, Zofran ODT, Aloxi, More.

Follow your doctor's dosing instructions very carefully. The first dose is usually taken before the start of your surgery, chemotherapy, or radiation treatment.

you are allergic to ondansetron or similar medicines (dolasetron, granisetron, palonosetron).

Pregnancy Category B No proven risk in humans.

Call your doctor for medical advice about side effects.

Zofran & Zuplenz Risks Anti-Nausea Drug Used During Pregnancy

3.3.2017 | Jessica MacAdam

Zofran and Zuplenz are prescription drugs used to treat nausea related to surgeries, cancer treatment and pregnancy. The drug has been prescribed for off-label.

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The Zuplenz package insert also notes that for patients with severely impaired liver function, the total daily dose of Zuplenz should not exceed 8 mg.

Other Zofran generic equivalent products have been approved by the FDA and have been available in the U.S. 3. since 2006.

As stated in the package insert, the recommended adult oral dosage of Zofran for the prevention of nausea and vomiting associated with chemotherapy ranges from one 8 mg tablet or 10 mL of oral solution twice daily to three 8 mg tablets administered 30 minutes before the start of single-day chemotherapy, depending on the emetogenic potential (moderate or high, respectively) of the chemotherapy.

You should provide your physician a complete list of the medications you currently take or plan to begin taking; this list should include all of your prescription drugs plus all of your over-the-counter drugs, including vitamins and nutritional supplements.