This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Drug interactions may change how your medications work or increase your risk for serious side effects. Do not start, stop, or change the dosage of any medicines without your doctor's approval.
In the US.
Many people using this medication do not have serious side effects. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects.
Ask your pharmacist about using those products safely. Check the labels on all your medicines (such as allergy or cough -and-cold products) because they may contain ingredients that cause drowsiness.
You may take this drug with or without food. If you have nausea, it may help to take this drug with food. Take this medication by mouth as directed by your doctor. Ask your doctor or pharmacist about other ways to decrease nausea (such as lying down for 1 to 2 hours with as little head movement as possible).
Do not use a household spoon because you may not get the correct dose. If you are using a liquid form of this medication, use a medication measuring device to carefully measure the prescribed dose.
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See also Warning section.
If you notice other effects not listed above, contact your doctor or pharmacist. This is not a complete list of possible side effects.
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l your doctor if your pain persists or worsens.
Ask your doctor or pharmacist about using this product safely. Caution is advised if you have diabetes, alcohol dependence, liver disease, or any other condition that requires you to limit/avoid these substances in your diet. Liquid products may contain sugar and alcohol.
If you wait until the pain has worsened, the medication may not work as well. Pain medications work best if they are used as the first signs of pain occur.
Other medications can affect the removal of hydrocodone / acetaminophen from your body, which may affect how hydrocodone/acetaminophen works. Examples include azole antifungals (such as ketoconazole ), macrolide antibiotics (such as erythromycin ), HIV medications (such as ritonavir ), rifamycins (such as rifabutin, rifampin ), certain drugs used to treat seizures (such as carbamazepine, phenytoin), among others.
Hydrocodone works in the brain to change how your body feels and responds to pain. This combination medication is used to relieve moderate to severe pain. It contains an opioid ( narcotic ) pain reliever ( hydrocodone ) and a non-opioid pain reliever ( acetaminophen ). Acetaminophen can also reduce a fever.
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The risk of serious side effects (such as slow/shallow breathing, severe drowsiness/ dizziness ) may be increased if this medication is taken with other products that may also cause drowsiness or breathing problems. l your doctor or pharmacist if you are taking other products such as other opioid pain or cough relievers (such as codeine, oxycodone ), alcohol, drugs for sleep or anxiety (such as alprazolam, lorazepam, zolpidem), muscle relaxants (such as carisoprodol, cyclobenzaprine ), or antihistamines (such as cetirizine, diphenhydramine ).
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Before taking this medication, l your doctor or pharmacist if you are allergic to it; or to other opioids (such as hydromorphone, morphine, codeine); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Children may be more sensitive to the side effects of this drug, especially slow/shallow breathing.
Consult your doctor before breast -feeding. This medication passes into breast milk and may rarely have undesirable effects on a nursing infant. l the doctor right away if your baby develops unusual sleepiness, difficulty feeding, or trouble breathing.
Overdose symptoms may include nausea, vomiting, loss of appetite, sweating, stomach / abdominal pain, extreme tiredness, yellowing eyes / skin, and dark urine. Get medical help right away if you take too much acetaminophen ( overdose ), even if you feel well.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.
If someone accidentally swallows this drug, get medical help right away. Keep this medicine in a safe place to prevent theft, misuse, or abuse.
See also Warning section.
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One ingredient in this product is acetaminophen. Ask your doctor or pharmacist how much acetaminophen is safe to take. Adults should not take more than 4000 milligrams (4 grams) of acetaminophen a day. People with liver problems and children should take less acetaminophen. Taking too much acetaminophen may cause serious (possibly fatal) liver disease.
Before using this medication, l your doctor or pharmacist your medical history, especially of: brain disorders (such as head injury, tumor, seizures ), breathing problems (such as asthma, sleep apnea, chronic obstructive pulmonary disease - COPD ), kidney disease, liver disease, mental/ mood disorders (such as confusion, depression, thoughts of suicide ), personal or family history of regular use/abuse of drugs/alcohol, stomach /intestinal problems (such as blockage, constipation, diarrhea due to infection, paralytic ileus), difficulty urinating (such as due to enlarged prostate ), gallbladder disease, disease of the pancreas ( pancreatitis ).
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In that case, this medication might be used for sudden (breakthrough) pain only as needed. Other pain relievers (such as ibuprofen, naproxen ) may also be prescribed. Ask your doctor or pharmacist about using this product safely with other drugs. If you have ongoing pain (such as due to cancer ), your doctor may direct you to also take long-acting opioid medications.
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Also, using it for a long time or in high doses near the expected delivery date may harm the unborn baby. To lessen the risk, take the smallest effective dose for the shortest possible time. During pregnancy, this medication should be used only when clearly needed. l your doctor if you are pregnant or if you plan to become pregnant. Babies born to mothers who use this drug for a long time may develop severe (possibly fatal) withdrawal symptoms. It may slightly increase the risk of birth defects if used during the first two months of pregnancy. l the doctor right away if you notice any symptoms in your newborn baby such as crying that doesn't stop, slow/shallow breathing, irritability, shaking, vomiting, diarrhea, poor feeding, or difficulty gaining weight. Before using this medication, women of childbearing age should talk with their doctor(s) about the risks and benefits.
If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. US residents can call their local poison control center at. Canada residents can call a provincial poison control center. Otherwise, call a poison control center right away. Symptoms of overdose may include: slow/shallow breathing, nausea, vomiting, loss of appetite, sweating, stomach / abdominal pain, extreme tiredness, slow heartbeat, yellowing eyes / skin, dark urine, coma.
This product is not recommended for use in children younger than 6 years due to an increased risk of serious side effects (such as slow/shallow breathing).
Get medical help right away if any of these very serious side effects occur: slow/shallow breathing, unusual lightheadedness, severe drowsiness/ dizziness, difficulty waking up. Taking this medication with alcohol or other drugs that can cause drowsiness or breathing problems may cause very serious side effects, including death. Hydrocodone / acetaminophen has a high risk for abuse and severe, possibly fatal, breathing problems. The risk for harm is higher when you start this medication and after a dose increase, or if you take the wrong dose/strength. To lower your risk, your doctor should have you take the smallest dose of hydrocodone/acetaminophen that works, and take it for the shortest possible time. See also Drug Interactions section. Be sure you know how to take hydrocodone/acetaminophen and what other drugs you should avoid taking with it.
Older adults may be more sensitive to the side effects of this drug, especially confusion, dizziness, drowsiness, and slow/shallow breathing.
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This drug may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Avoid alcoholic beverages.
Daily alcohol use, especially when combined with acetaminophen, may damage your liver. Avoid alcohol.
Do not use it later for another condition unless your doctor directs you to do so. A different medication may be necessary in that case. This medication has been prescribed for your current condition only.
The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.
This medication may cause withdrawal reactions, especially if it has been used regularly for a long time or in high doses. In such cases, withdrawal symptoms (such as restlessness, watering eyes, runny nose, nausea, sweating, muscle aches) may occur if you suddenly stop using this medication. To prevent withdrawal reactions, your doctor may reduce your dose gradually. Ask your doctor or pharmacist for more details, and report any withdrawal reactions right away.
A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching /swelling (especially of the face/ tongue /throat), severe dizziness, trouble breathing.
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Check the labels on all your medicines to see if they contain acetaminophen, and ask your pharmacist if you are unsure. Acetaminophen is in many nonprescription and prescription medications (such as pain/fever drugs or cough -and-cold products). Do not use with any other drug containing acetaminophen without asking your doctor or pharmacist first.
Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.Information last revised November 2016. Properly discard this product when it is expired or no longer needed. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. 2016 First Databank, Inc.
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Some products that may interact with this drug include: certain pain medications (mixed opioid agonist/antagonists such as pentazocine, nalbuphine, butorphanol), opioid antagonists (such as naltrexone, naloxone ).
l your doctor right away if you have any serious side effects, including: mental/mood changes (such as agitation, confusion, hallucinations ), stomach / abdominal pain, difficulty urinating, signs of your adrenal glands not working well (such as loss of appetite, unusual tiredness, weight loss ).
When this medication is used for a long time, it may not work as well. Talk with your doctor if this medication stops working well.
Before having surgery, l your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).
During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor. It may harm an unborn baby.
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Nausea, vomiting, constipation, lightheadedness, dizziness, or drowsiness may occur. If any of these effects persist or worsen, l your doctor or pharmacist promptly. Some of these side effects may decrease after you have been using this medication for a while.
Keep all medications away from children and pets. Check the product package for instructions on how to store your brand, or ask your pharmacist. Store at room temperature away from light and moisture. Different brands of this medication have different storage needs.
Along with its benefits, this medication may rarely cause abnormal drug-seeking behavior ( addiction ). This risk may be increased if you have abused alcohol or drugs in the past. Take this medication exactly as prescribed to lessen the risk of addiction.
If you are taking this product on a regular schedule and miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.
See also Warning section.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at.
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See also Warning section.
The dosage is based on your medical condition and response to treatment. Do not increase your dose, take the medication more frequently, or take it for a longer time than prescribed. In children, the dosage is also based on weight. Properly stop the medication when so directed.
Make sure laboratory personnel and all your doctors know you use this drug. This medication may interfere with certain laboratory tests (including amylase / lipase levels), possibly causing false test results.
Get medical help right away if you have any very serious side effects, including: fainting, seizure, slow/shallow breathing, severe drowsiness/difficulty waking up.
If you have any questions, ask your doctor or pharmacist. Read the Medication Guide and, if available, the Patient Information Leaflet provided by your pharmacist before you start taking this medication and each time you get a refill.
To prevent constipation, eat a diet adequate in fiber, drink plenty of water, and exercise. Consult your pharmacist for help in selecting a laxative (such as a stimulant type with stool softener ).
To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position.Hydrocodone