Aldactone (spironolactone) tablets, USP. WARNING. ALDACTONE has been shown to be a tumorigen in chronic toxicity studies in rats (see.
Metabolism: Hyperkalemia, electrolyte disturbances (see WARNINGS and PRECAUTIONS ). Musculoskeletal: Leg cramps.
For patients who are considered unsuitable for surgery, ALDACTONE may be employed for long-term maintenance therapy at the lowest effective dosage determined for the individual patient. After the diagnosis of hyperaldosteronism has been established by more definitive testing procedures, ALDACTONE may be administered in doses of 100 to 400 mg daily in preparation for surgery.
Short-term preoperative treatment of patients with primary hyperaldosteronism.
Skeletal muscle relaxants, nondepolarizing (e.g., tubocurarine): Possible increased responsiveness to the muscle relaxant may result.
Alcohol, barbiturates, or narcotics: Potentiation of orthostatic hypotension may occur.
ALDACTONE (spironolactone) is indicated in the management of: Primary hyperaldosteronism for:
ALDACTONE in a dosage ranging from 25 mg to 100 mg daily is useful in treating a diuretic-induced hypokalemia, when oral potassium supplements or other potassium-sparing regimens are considered inappropriate.
Digestive: Gastric bleeding, ulceration, gastritis, diarrhea and cramping, nausea, vomiting.
ALDACTONE is indicated for maintenance therapy together with bed rest and the restriction of fluid and sodium.
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Drowsiness, dizziness, lightheadedness, stomach upset, diarrhea, nausea, vomiting, or headache may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. To minimize lightheadedness, get up slowly when rising from a seated or lying position.
Inform your doctor if your condition worsens (e.g., if you notice an increase in your routine blood pressure readings ).
If you miss a dose, take it as soon as you remember.
Spironolactone is a potassium-sparing diuretic (water pill) that prevents your body from absorbing too much sodium and keeps your potassium levels from getting too low. Spironolactone also treats fluid retention (edema) in people with congestive heart failure, cirrhosis of the.
100 to 400 mg/day orally in 1 or 2 divided doses.
Usual Pediatric Dose for Hypertension:
CSA Schedule N Not a controlled drug.
Be careful if you drive or do anything that requires you to be alert. Spironolactone may impair your thinking or reactions.
Usual Adult Dose for Congestive Heart Failure:
If you are being treated for high blood pressure, keep using this medication even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medication for the rest of your life.
Children: 100 to 400 mg/m2/day orally in 1 to 2 divided doses.
dizziness, headache, mild drowsiness; leg cramps; or.
Spironolactone is a potassium-sparing diuretic (water pill) that prevents your body from absorbing too much sodium and keeps your potassium levels from getting too low.
Approval History Calendar Drug history at FDA.
25 to 200 mg/day orally in 1 or 2 divided doses.
Usual Pediatric Dose for Primary Hyperaldosteronism Diagnosis:
Stop using spironolactone and call your doctor at once if you have:
breast swelling or tenderness;
Neonates: 1 to 3 mg/kg/day orally every 12 to 24 hours.
Studies dating back to the 1980s have demonstrated the efficacy of spironolactone for acne in women, particularly acne unresponsive to.
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In general, spironolactone is well tolerated, and side effects tend to be dose-dependent, said Schlosser. A survey of 91 patients who received spironolactone for acne showed that the most common adverse events were diuresis (29%) and menstrual irregularities (22%), followed by breast tenderness (17%), fatigue (15%), and dizziness and lightheadedness (11% to 12%).
Patients' adherence to contraception should be monitored, along with pregnancy testing.
Spironolactone: learn about side effects, dosage, special precautions, and more on MedlinePlus.
If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online ( http://www.fda.gov/Safety/MedWatch ) or by phone.
AHFS Patient Medication Information., 2017. The American Society of Health-System Pharmacists, Inc., 7272 Wisconsin Avenue, Bethesda, Maryland. Duplication for commercial use must be authorized by ASHP.
It causes the kidneys to eliminate unneeded water and sodium from the body into the urine, but reduces the loss of potassium from the body.