(See WARNINGS: Clinical Worsening and Suicide Risk, PRECAUTIONS: Information for Patients, and PRECAUTIONS: Pediatric Use.) Paxil (paroxetine hydrochloride) is an orally administered psychotropic drug. Each film‑coated tablet contains paroxetine hydrochloride equivalent to.
Study 2 was a flexible‑dose study comparing paroxetine (20 mg to 50 mg daily) and placebo. A third study, also flexible-dose comparing paroxetine (20 mg to 50 mg daily), did not demonstrate statistically significant superiority of Paxil over placebo on the Hamilton Rating Scale for Anxiety (HAM‑A) total score, the primary outcome. Paxil demonstrated statistically significant superiority over placebo on the Hamilton Rating Scale for Anxiety (HAM‑A) total score.
In vitro radioligand binding studies indicate that paroxetine has little affinity for muscarinic, alpha 1 -, alpha 2 -, beta-adrenergic-, dopamine (D 2 )-, 5‑HT 1 -, 5‑HT 2 -, and histamine (H 1 )‑receptors; antagonism of muscarinic, histaminergic, and alpha 1 -adrenergic receptors has been associated with various anticholinergic, sedative, and cardiovascular effects for other psychotropic drugs.
Find patient medical information for Paxil CR Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings.
Ask your doctor when to start or stop taking this medication. Avoid taking MAO inhibitors ( isocarboxazid, linezolid, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, selegiline, tranylcypromine ) during treatment with this medication. Taking MAO inhibitors with this medication may cause a serious (possibly fatal) drug interaction. Most MAO inhibitors should also not be taken for two weeks before and after treatment with this medication.
Do not share this medication with others.
l your doctor right away if you have any serious side effects, including: shaking (tremor), restlessness, inability to keep still, decreased interest in sex, changes in sexual ability, numbness/tingling, easy bruising/bleeding, fast/ irregular heartbeat, muscle weakness/spasm, seizures.
It may take up to several weeks before you get the full benefit of this drug.
See also Warning section.
Keep all regular medical and psychiatric appointments.
Monitor weight and height in children who are taking this drug.
That's why TV ads for Paxil caught my eye. You've seen them: They promise ease in a pill. An end to social anxiety. Does my degree of shyness.
Have I suffered from depression? I've been blue but nothing serious. The Transformation Day 1: After taking my blood pressure, the doc sits me down and asks a few questions. Am I shy? Yes, I'm uncomfortable speaking in groups. I l him I've taken the self-test at Paxil.com (example: "I avoid having to give speeches—Not at all, A little bit, Somewhat, Very much, or Extremely") and it said, "Your score suggests that you may be experiencing the symptoms of social anxiety disorder." Of course, it wouldn't surprise me if it always said that.
Paxil (paroxetine) is an antidepressant belonging to a group of drugs called selective serotonin reuptake inhibitors (SSRIs). Paroxetine affects chemicals in the brain that may be unbalanced in people with depression, anxiety, or other disorders. Paxil is used to treat depression.
migraine headache medicine - sumatriptan, rizatriptan, zolmitriptan, and others; or.
Paxil may also be used for purposes not listed in this medication guide.
seizure medicine - phenobarbital, phenytoin.
severe nervous system reaction - very stiff (rigid) muscles, high fever, sweating, confusion, fast or uneven heartbeats, tremors, fainting; or.
heart disease, high blood pressure, history of stroke;
low levels of sodium in the body - headache, confusion, slurred speech, severe weakness, loss of coordination, feeling unsteady;
racing thoughts, decreased need for sleep, unusual risk-taking behavior, feelings of extreme happiness or sadness, being more talkative than usual;
This is not a complete list of side effects and others may occur.
Besides treating depression, the antidepressant Paxil may affect personality traits in positive ways, a new study suggests.
News release, Northwestern University.
“They traditionally think of as antidepressants first and foremost, and the effect on personality as negligible or by-products of depression improvements,” Yang says. “We are now finding that the effect on personality is very substantial and clearly not a by-product of depression improvement.”. “To most psychiatrists our findings would be very surprising,” he says.
Extraversion refers to being inclined to have positive emotions, assertiveness, and gregariousness.
All patients showed less depression at week 8, the researchers report in the December issue of Archives of General Psychiatry.
In addition, he ls WebMD, the patients in the Paxil group became more extraverted, meaning they became more open to new experiences, calmer, less self-conscious, and more even-tempered.
Then there was a 12-month phase when half of those in the Paxil group stayed on Paxil and half were taken off Paxil and given placebo pills.